초기임상시험 전문 의료진

초기임상시험 및 임상약리연구에 대한 최적화된 서비스 제공 합니다.

초기임상시험 및 임상약리연구에 대한 전문의료진

조두연 교수

가정의학과

상세소개
연구분야
초기임상시험, 건강기능성식품 인체적용시험
연구경험
  • Drug-drug interaction studies
  • Comparative pharmacokinetic studies
  • First-in-Human Studies (Alzheimer’s disease, Fatigue)
  • Gastric pH monitoring studies
  • Genotype-based PK/PD studies
주요연구 실적
SCI 논문 27편(주저자 8편)
  • Cho DY, Shen JH, Lemler SM, Skaar TC, Li L, Blievernicht J, Zanger UM, Kim KB, Shin JG, Flockhart DA, Desta Z. Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers. Drug Metab Pharmacokinet. 2016;31(2):107-16.
  • Oh M, Yoon J, Cho DY. Pharmacokinetic and Pharmacodynamic Comparison of Two Recombinant Human Erythropoietin Formulations, PDA10 and Eprex, in Healthy Korean Male Volunteers: A Randomized, Double-Blinded, Single-Dose, Two-Period Crossover Study. Clin Drug Investig. 2015; 35(10):659-64.
  • Cho DY, Bae SH, Lee JK, Park JB, Kim YW, Lee S, Oh E, Kim BT, Bae SK. Effect of the potent CYP2D6 inhibitor sarpogrelate on the pharmacokinetics and pharmacodynamics of metoprolol in healthy male Korean volunteers. 2015;45(3):256-63.

임경수 교수

임상약리학과

상세소개
연구분야
신약개발 초기임상시험, 개인별 맞춤약물요법 자문
연구경험
네덜란드 Centre for Human Drug Research 에서 1년간 연수, FDA 및 EMEA 허가용 초기임상시험 project leader 경험
First-in-Human Studies (Endometriosis, Parkinson’s disease etc)
주요연구 실적
SCI 논문 60여 편(주저자 12편)
  • Han HK, Ahn H, Shin KH, Shin D, Lee SH, Kim JH, Cho SH, Kang HR, Jang IJ, Yu KS, Lim KS. Trough concentration over 12.1 mg/L is a major risk factor of vancomycin-related nephrotoxicity in patients with therapeutic drug monitoring. Ther Drug Monit. 2014 Oct;36(5):606-11
  • Park MK, Kim TE, Kim JW, Kim C, Yoon SH, Cho JY, Jang IJ, Yu KS, Lim KS. Tolerability and pharmacokinetics of lobeglitazone, a novel PPAR gamma agonist, after a single oral administration in healthy female subjects. Clin Drug Investig. 2014 Jul;34(7):467-74
  • Jeon HW, Jang IJ, Lee S, Ohashi K, Kotegawa T, Ieiri I, Cho JY, Yoon SH, Shin SG, Yu KS, Lim KS. Apple juice greatly reduces systemic exposure to atenolol. Br J Clin Pharmacol. 2013 Jan;75(1):172-9

김민경 교수

정신건강의학과

상세소개
연구분야
초기임상시험, 중추신경계 약물 연구
연구경험
Drug-Drug interaction studies comparative pharmacokinetic studies
First-in-Human Studies (Parkinson’s Disease)
주요연구 실적
SCI 논문 12편(주저자 4편)
  • Kim MK, Kim BR, Lee KS, Kim CM, Bang SY, Choi TK, Lee SH. White-matter connectivity related to paliperidone treatment response in patients with schizophrenia. Journal of Psychopharmacology. Vol. 30, pp. 294-302, 2016
  • Kim MK, Kim BR, Choi TK, Lee SH. White Matter Correlates of Anxiety Sensitivity in Panic Disorder. Affect Disord. Vol. 207, pp. 148-156, 2016
  • Jang KH*, Kim MK*, Oh JS, Lee SH, Cho JY, Yu KS, Choi TK, Lee SH, Lim KS. Effects of dexamethasone co-administered with oseltamivir on the pharmacokinetics of oseltamivir in healthy volunteers. Drug Design, Development and Therapy (In Press)
  • Yu ST*, Kim MK*, Kim BR, Yoo EH, Lee JY, Lee KS, Choe AY, Yook KH, Choi TK, Lee SH. The Effects of 5-HTR1A Polymorphism on Cingulum Connectivity in Patients with Panic Disorder. Psychiatry Investigation Vol. 10, No. 4, pp.399-406, 2013